Heck Coupling Styrene with Aryl Halides Catalyzed by Palladium Complexes in Biphasic Media

نویسندگان

  • Khemais Saïd
  • Younes Moussaoui
  • Ridha Ben Salem
چکیده

* corresponding author, e-mail: [email protected] ; tel : (216) 74276400 ; fax : (216) 74274437 ABSTRACT: In this work, we have studied the effect of the halide nature in the coupling of styrene with halide benzene catalysed by palladium acetate or chloride. The activation by a catalyst of phase-transfer type Aliquat-336 improves the reactivity in N, N-dimethylformamide-water mixture. The presence of electron-donating groups on the aromatic nucleus of aryl halide involves a decrease of yields. We have also tested the effectiveness of the catalytic system PdCl{C6H3-2,6-(OP i Pr2)2} in the coupling of styrene with aromatic chlorides. In this context, a reactional mechanism is proposed.

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تاریخ انتشار 2009